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Clinical Pipeline

Wide landscape pipeline table graphic showing ALX-001 program rows

Clinical Development Status

Allyx Therapeutics is advancing ALX-001, a first-in-class synapse-targeting therapy, through rigorous clinical investigations to address the core pathology of neurodegeneration.

Alzheimer's Disease

Status: Phase 2 Ready

Following successful Phase 1b results, ALX-001 is advancing into Phase 2 studies to evaluate impact on synaptic health.

Parkinson's Disease

Status: Phase 1b Completed

Clinical expansion into Parkinson's is underway, with the first patient recently treated under our IND application.

Program FUNDING

Supported in Part By:

Our Studies

Extensive Phase 1 safety, tolerability, pharmacokinetics, and target engagement package to support Phase 2 studies.

NCT-06632990

A Study Evaluating the Potential of ALX-001 (BMS-984923) to Alter the Systemic Exposure of Three Orally Adminsitered Probe Subtrates

Phase 1

Alzheimer's Disease / Parkinson's Disease

NCT-06309147

Evaluating the Safety of ALX-001 (BMS-984923) in Patients with Parkinson's Disease

Phase 1

Parkinson's Disease

NCT-05804383

A Multiple Ascending Dose Study in healthy Volunteers and Patients with Alzheimer's Disease.

Phase 1

Alzheimer's Disease

NCT-05817643

Food Effect Study of ALX-001 (BMS-984923) in Healthy Older Adults.

Phase 1

Alzheimer's Disease / Parkinson's Disease

NCT-04805983

Evaluating the Safety, Tolerability, Pharmacokinetics and Receptor Occupancy of BMS-984923

Phase 1

Alzheimer's Disease / Parkinson's Disease

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